Wilson’s disease

Definition

Wilson's disease is a genetic disorder characterized by excessive accumulation of copper in the liver, brain, and other vital organs. It can lead to neurological and psychiatric symptoms if not properly managed.

5 Must Know Facts For Your Next Test

1. Wilson's disease is diagnosed through a combination of blood tests, urine tests, and liver biopsy.
2. Common neurological symptoms include tremors, difficulty speaking, and impaired coordination.
3. Copper chelation therapy and zinc supplementation are primary treatments for managing Wilson's disease.
4. Dietary adjustments to avoid copper-rich foods are crucial for patients with Wilson's disease.
5. Early diagnosis and treatment are essential to prevent irreversible organ damage due to copper buildup.

Review Questions

• What are the primary diagnostic methods for Wilson's disease?
• Which treatments are commonly used to manage Wilson's disease?
• Why is it important for patients with Wilson's disease to avoid copper-rich foods?

Related terms

Chelation Therapy:

A treatment that involves the administration of agents to remove heavy metals from the body.

Hepatolenticular Degeneration: Another term used synonymously with Wilson’s disease, emphasizing its impact on the liver and brain.

Zinc Supplementation: The use of zinc supplements to block the absorption of copper in patients with Wilson’s disease.