Warfarin

Definition

Warfarin is an anticoagulant medication used to prevent and treat blood clots. It works by inhibiting the synthesis of vitamin K-dependent clotting factors in the liver.

5 Must Know Facts For Your Next Test

1. Warfarin's efficacy can be affected by dietary intake of vitamin K, which is found in green leafy vegetables.
2. Patients on warfarin require regular blood tests to monitor their International Normalized Ratio (INR) levels.
3. Certain medications and supplements can interact with warfarin, altering its effectiveness or increasing the risk of bleeding.
4. Warfarin has a narrow therapeutic range, meaning that maintaining the correct dosage is critical to avoid complications.
5. Alcohol consumption can affect warfarin metabolism and should be discussed with a healthcare provider.

Review Questions

• How does dietary vitamin K intake impact the effectiveness of warfarin?
• Why is it important for patients on warfarin to regularly monitor their INR levels?
• What are some potential risks associated with incorrect dosing of warfarin?

Related terms

Heparin: An anticoagulant medication often used for short-term treatment to prevent blood clots.

INR (International Normalized Ratio): A standardized measure used to determine the clotting tendency of blood, particularly important for patients on warfarin.

Vitamin K:

A fat-soluble vitamin essential for blood clotting; high intake can reduce the effectiveness of warfarin.