Nanostring Technologies

Definition

Nanostring Technologies is a biotechnology company that specializes in the development of molecular diagnostic tools based on its proprietary nCounter® Analysis System. This system allows for the precise measurement of nucleic acids and proteins at the nanoscale, enabling researchers to conduct high-throughput genomic studies and analyze complex biological systems with unprecedented accuracy.

5 Must Know Facts For Your Next Test

1. Nanostring Technologies focuses on providing solutions for cancer research, immunology, and infectious disease studies through their innovative platforms.
2. The nCounter® system allows researchers to analyze up to 800 genes in a single assay, streamlining workflows and reducing time compared to traditional methods.
3. One key feature of Nanostring's technology is its ability to analyze formalin-fixed, paraffin-embedded (FFPE) samples, which are commonly used in clinical settings.
4. Nanostring's products enable both targeted gene expression analysis and multiplex protein detection, making them versatile tools for researchers.
5. Intellectual property surrounding Nanostring Technologies includes patents for their unique digital barcoding methods and applications in various fields such as diagnostics and therapeutics.

Review Questions

• How does the nCounter® Analysis System improve the accuracy of gene expression studies compared to traditional methods?
  • The nCounter® Analysis System enhances accuracy by utilizing digital barcoding technology, which allows for simultaneous measurement of multiple targets within a single sample. This method minimizes the variability associated with amplification steps found in traditional PCR-based techniques. Additionally, the nCounter® system provides quantitative results without requiring reverse transcription or amplification, leading to more reliable data from challenging samples.
• Discuss the impact of Nanostring Technologies on cancer research and diagnostics through its innovative platforms.
  • Nanostring Technologies has significantly impacted cancer research by providing tools that enable precise measurement of gene expression profiles associated with various tumors. Their nCounter® system allows researchers to identify specific biomarkers that can inform treatment decisions. Additionally, the ability to analyze FFPE samples facilitates the use of existing clinical specimens for research purposes, enhancing the translation of findings into clinical practice and improving patient outcomes.
• Evaluate how the intellectual property landscape surrounding Nanostring Technologies influences its market position and competitive advantage in biotechnology.
  • The intellectual property landscape is crucial for Nanostring Technologies as it protects their innovations, including unique methodologies and applications in diagnostics. By securing patents for their digital barcoding technology, Nanostring can maintain a competitive edge over other companies in the biotechnology sector. This protection not only fosters continued investment in research and development but also enhances collaboration opportunities with academic institutions and healthcare organizations, ultimately solidifying their market position.

Related terms

nCounter® Analysis System: A platform developed by Nanostring Technologies that enables the simultaneous measurement of hundreds of genes or proteins in a single sample using digital barcoding technology.

Digital Spatial Profiling: A technique that utilizes Nanostring's technology to analyze protein expression and localization within tissue sections, providing insights into spatial biology.

RNA Sequencing: A method used to determine the quantity and sequences of RNA in a sample, which can be compared with Nanostring’s technologies for comprehensive gene expression analysis.