Whooping cough

Definition

Whooping cough, also known as pertussis, is a highly contagious bacterial infection of the respiratory tract caused by Bordetella pertussis. It is characterized by severe coughing fits followed by a high-pitched 'whoop' sound during inhalation.

5 Must Know Facts For Your Next Test

1. Whooping cough is caused by the Gram-negative bacterium Bordetella pertussis.
2. The DTaP vaccine protects against whooping cough, diphtheria, and tetanus.
3. Bordetella pertussis produces several toxins that damage the respiratory tract and lead to the characteristic symptoms of whooping cough.
4. Infants are at the highest risk for severe complications from whooping cough, including pneumonia and death.
5. Laboratory diagnosis of whooping cough often involves polymerase chain reaction (PCR) testing or culture from nasopharyngeal swabs.

Review Questions

• What bacterium is responsible for causing whooping cough?
• Which vaccine is used to prevent whooping cough in children?
• What are the typical clinical features of whooping cough?

Related terms

Bordetella pertussis:

A Gram-negative bacterium that causes whooping cough.

DTaP Vaccine: A combination vaccine that protects against diphtheria, tetanus, and pertussis.

Respiratory Tract Infection: An infection occurring in any part of the respiratory system, including diseases such as bronchitis, pneumonia, and influenza.