Thrombi

Definition

Thrombi are clots formed within the blood vessels due to the aggregation of platelets, fibrin, and other cellular elements. They can impede blood flow and cause complications like stroke or heart attack.

5 Must Know Facts For Your Next Test

1. Thrombi can form in arteries or veins, leading to arterial or venous thrombosis respectively.
2. Bacteria such as Staphylococcus aureus can induce thrombus formation by damaging endothelial cells and triggering an immune response.
3. Infective endocarditis is a condition where bacterial infection leads to the formation of thrombi on heart valves.
4. Septicemia can result in disseminated intravascular coagulation (DIC), a severe condition characterized by widespread thrombus formation.
5. Antibiotics and anticoagulants are commonly used treatments to manage bacterial infections associated with thrombi.

Review Questions

• What types of bacteria are commonly associated with thrombus formation?
• How do bacterial infections contribute to the development of thrombi in the circulatory system?
• What are common complications arising from untreated thrombi?

Related terms

Endocarditis:

Inflammation of the inner lining of the heart, often involving infection and thrombus formation.

Septicemia:

A serious bloodstream infection that can lead to widespread inflammation and thrombosis.

Disseminated Intravascular Coagulation (DIC): A condition characterized by excessive clotting throughout the body, often triggered by severe infections.