Systemic autoimmune disease

Definition

A systemic autoimmune disease is a condition where the immune system mistakenly attacks the body's own tissues, affecting multiple organs or systems. These diseases can lead to chronic inflammation and damage in various parts of the body.

5 Must Know Facts For Your Next Test

1. Systemic autoimmune diseases often involve autoantibodies that target self-antigens.
2. Common examples include systemic lupus erythematosus (SLE), rheumatoid arthritis, and scleroderma.
3. Genetic predisposition, environmental factors, and infections are known triggers for these diseases.
4. Diagnosis typically involves a combination of clinical symptoms, laboratory tests, and imaging studies.
5. Treatment usually includes immunosuppressive drugs to reduce immune system activity.

Review Questions

• What are some common examples of systemic autoimmune diseases?
• How do genetic and environmental factors contribute to the onset of systemic autoimmune diseases?
• What types of treatments are typically used for managing systemic autoimmune diseases?

Related terms

Autoantibody: An antibody produced by the immune system that targets an individual's own proteins or tissues.

Chronic Inflammation:

Prolonged inflammation that can result in tissue damage and contribute to various chronic conditions.

Immunosuppressive Drugs: Medications that inhibit or prevent activity of the immune system, used in treating autoimmune diseases.