Sporulation is the process by which certain bacteria form endospores, allowing them to survive in harsh environmental conditions. This is a key survival mechanism for some prokaryotic cells.
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Sporulation occurs in response to nutrient deprivation or other environmental stresses.
Endospores are highly resistant to heat, radiation, and chemical disinfectants.
The process of sporulation includes several stages: replication of DNA, formation of a spore septum, engulfment of the forespore, and maturation.
Bacillus and Clostridium are two genera of bacteria that commonly undergo sporulation.
Sporulated cells can remain dormant for extended periods until favorable conditions return.