Reactive arthritis

Definition

Reactive arthritis is an autoimmune condition triggered by infections, often involving the gastrointestinal or urogenital tract. It typically presents with joint inflammation following a bacterial infection.

5 Must Know Facts For Your Next Test

1. Reactive arthritis often occurs after infections caused by bacteria such as Salmonella, Shigella, Yersinia, and Campylobacter.
2. Symptoms include pain and swelling in joints, usually knees, ankles, and feet.
3. It is associated with other symptoms like conjunctivitis and urethritis.
4. The HLA-B27 gene is found in a significant number of individuals with reactive arthritis.
5. Treatment focuses on managing symptoms through anti-inflammatory medications and physical therapy.

Review Questions

• Which bacteria are commonly linked to triggering reactive arthritis?
• What are the hallmark symptoms of reactive arthritis?
• How does the HLA-B27 gene relate to reactive arthritis?

Related terms

Salmonella:

A genus of bacteria that can cause foodborne illness and is known to trigger reactive arthritis.

Conjunctivitis:

Inflammation or infection of the outer membrane of the eyeball and the inner eyelid, sometimes seen in cases of reactive arthritis.

HLA-B27: A genetic marker that increases susceptibility to several autoimmune diseases including reactive arthritis.