Prednisone

Definition

Prednisone is a synthetic corticosteroid drug commonly used to reduce inflammation and suppress the immune system. It is often prescribed for conditions involving hypersensitivities and autoimmune diseases.

5 Must Know Facts For Your Next Test

1. Prednisone can be used to treat severe allergic reactions by reducing inflammation.
2. Long-term use of prednisone can lead to side effects such as immunosuppression and increased susceptibility to infections.
3. Prednisone mimics the effects of cortisol, a hormone naturally produced by the adrenal glands.
4. It is frequently used in managing chronic conditions like asthma, rheumatoid arthritis, and lupus.
5. Abrupt discontinuation of prednisone can lead to withdrawal symptoms; it must be tapered off gradually under medical supervision.

Review Questions

• What are the primary medical uses of prednisone in treating hypersensitivities?
• Why must prednisone be tapered off gradually rather than stopped abruptly?
• How does prednisone affect the immune system when used long-term?

Related terms

Corticosteroids:

A class of steroid hormones that reduce inflammation and modulate immune function.

Autoimmune Disease: A condition where the immune system mistakenly attacks the body's own tissues.

Immunosuppression:

The reduction of the efficacy of the immune system's response, often induced by medication or disease.