Memory B cells

Definition

Memory B cells are a type of B lymphocyte that retains information about pathogens after an initial immune response, allowing for a faster and more efficient response upon re-exposure to the same pathogen. They play a crucial role in long-term immunity.

5 Must Know Facts For Your Next Test

1. Memory B cells are formed following the activation of naive B cells during an initial infection or vaccination.
2. They have a longer lifespan compared to plasma B cells, often persisting for years or even decades.
3. Upon re-exposure to the same antigen, memory B cells can quickly proliferate and differentiate into plasma cells that produce specific antibodies.
4. Memory B cells express surface immunoglobulin that is highly specific to the antigen encountered during the primary immune response.
5. These cells reside in secondary lymphoid organs such as the spleen and lymph nodes, where they can rapidly respond to subsequent infections.

Review Questions

• How do memory B cells differ from plasma B cells in terms of their function and lifespan?
• What role do memory B cells play upon re-exposure to a previously encountered pathogen?
• Where are memory B cells typically located within the body?

Related terms

Naive B Cells: Immature B lymphocytes that have not yet encountered their specific antigen.

Plasma Cells:

Effector B lymphocytes that produce large amounts of antibodies during an immune response.

Secondary Lymphoid Organs: Structures such as lymph nodes and spleen where immune responses are coordinated.