Microbiology

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Human herpesvirus 5 (HHV-5)

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Microbiology

Definition

Human herpesvirus 5 (HHV-5), also known as cytomegalovirus (CMV), is a common virus that can infect anyone. It is particularly significant in immunocompromised individuals and can cause serious complications.

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5 Must Know Facts For Your Next Test

  1. HHV-5 can remain dormant in the body and reactivate under certain conditions, such as weakened immunity.
  2. Primary infection with HHV-5 is often asymptomatic or presents with mild flu-like symptoms.
  3. Congenital CMV infection can lead to severe developmental disabilities and hearing loss in newborns.
  4. HHV-5 is commonly transmitted through bodily fluids such as saliva, blood, urine, semen, and breast milk.
  5. Diagnosis of HHV-5 infection may involve serology tests to detect specific antibodies or PCR tests to identify viral DNA.

Review Questions

  • What are the primary modes of transmission for human herpesvirus 5?
  • Why might HHV-5 present more severe complications in immunocompromised individuals?
  • How is congenital CMV infection diagnosed and what are its potential impacts?

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