Microbiology

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Hemolysin

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Microbiology

Definition

Hemolysin is a type of toxin produced by certain bacteria that can destroy red blood cells by disrupting their cell membrane. This action releases hemoglobin and can contribute to the pathogenicity of the bacterium.

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5 Must Know Facts For Your Next Test

  1. Hemolysins are typically classified as exotoxins and play a crucial role in bacterial virulence.
  2. They are often produced by pathogens such as Streptococcus, Staphylococcus, and Escherichia coli.
  3. Hemolytic activity can be assessed using blood agar plates, where clear zones around colonies indicate red blood cell lysis.
  4. In gastrointestinal infections, hemolysins can contribute to tissue damage and inflammation.
  5. Some hemolysins function by forming pores in the host cell membranes, leading to cell lysis.

Review Questions

  • What is the primary function of hemolysins in bacterial infections?
  • Which types of bacteria are known for producing hemolysins?
  • How can the presence of hemolysins be detected in a laboratory setting?

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