Hematopoietic stem cells

Definition

Hematopoietic stem cells are multipotent stem cells capable of differentiating into all types of blood cells, including T and B lymphocytes. They play a crucial role in the immune system by generating the cellular components necessary for adaptive immunity.

5 Must Know Facts For Your Next Test

1. Hematopoietic stem cells reside primarily in the bone marrow.
2. These stem cells can differentiate into both myeloid and lymphoid lineages.
3. They are essential for the production of T lymphocytes, which are important for cellular immunity.
4. They also differentiate into B lymphocytes, which are critical for humoral immunity.
5. Hematopoietic stem cell transplantation is a treatment for various blood disorders and immune deficiencies.

Review Questions

• Where are hematopoietic stem cells primarily located?
• What types of cells can hematopoietic stem cells differentiate into?
• How do hematopoietic stem cells contribute to adaptive immunity?

Related terms

Bone Marrow: The primary site where hematopoietic stem cells reside and differentiate.

T Lymphocytes:

Cells derived from hematopoietic stem cells that play a key role in cellular immunity.

B Lymphocytes:

Cells derived from hematopoietic stem cells that produce antibodies for humoral immunity.