Generalized transduction

Definition

Generalized transduction is a process by which bacteriophages transfer bacterial DNA from one bacterium to another during infection. This mechanism can result in genetic recombination in the recipient bacteria.

5 Must Know Facts For Your Next Test

1. Generalized transduction involves the accidental packaging of host bacterial DNA into a phage particle.
2. Any gene from the donor bacterium's genome can be transferred through generalized transduction.
3. Transducing phages lack specificity for which genes they transfer, unlike specialized transduction.
4. This process contributes to genetic diversity among prokaryotes despite their asexual reproduction.
5. The efficiency of generalized transduction depends on factors like the multiplicity of infection and the stability of the DNA in the recipient cell.

Review Questions

• What distinguishes generalized transduction from specialized transduction?
• How does generalized transduction contribute to genetic diversity in prokaryotes?
• What role do bacteriophages play in generalized transduction?

Related terms

Bacteriophage:

A virus that infects and replicates within bacteria.

Specialized Transduction:

A process where only specific portions of the bacterial genome are transferred by a lysogenic phage.

Conjugation:

A method of horizontal gene transfer where DNA is transferred between bacteria through direct contact.