F− cell

Definition

An F− cell is a bacterial cell that lacks the F (fertility) plasmid, which means it cannot initiate conjugation. It can receive genetic material from an F+ or Hfr cell during the process of bacterial conjugation.

5 Must Know Facts For Your Next Test

1. F− cells lack the F plasmid, also known as the fertility factor.
2. During conjugation, an F− cell can receive genetic material from an F+ or Hfr cell through a pilus.
3. The transfer of genetic material to an F− cell can result in genetic recombination and increased genetic diversity.
4. After conjugation with an F+ cell, the formerly F− cell may become an F+ cell if it receives a complete copy of the F plasmid.
5. F− cells are important in studies of horizontal gene transfer and antibiotic resistance.

Review Questions

• What distinguishes an F− cell from an F+ cell?
• How does conjugation contribute to genetic diversity in prokaryotes?
• What happens to an F− cell after successful conjugation with an Hfr strain?

Related terms

F+ Cell: A bacterial cell containing the fertility (F) plasmid, capable of initiating conjugation.

Hfr Cell: A high-frequency recombination bacterial strain where the F plasmid is integrated into the chromosomal DNA.

Conjugation Pilus: A structure used by bacteria to transfer DNA during conjugation.