Coenzyme A (CoA)

Definition

Coenzyme A (CoA) is a molecule that plays a crucial role in the metabolism of carbohydrates, fats, and proteins. It acts as a carrier of acyl groups in various biochemical reactions.

5 Must Know Facts For Your Next Test

1. Coenzyme A is essential for the formation of acetyl-CoA, which enters the citric acid cycle.
2. It participates in the synthesis and oxidation of fatty acids.
3. CoA is derived from pantothenic acid (vitamin B5).
4. It plays a key role in the transfer of acetyl groups during metabolic processes.
5. Its thioester bond with acyl groups makes it highly reactive and efficient in biochemical reactions.

Review Questions

• What role does Coenzyme A play in carbohydrate metabolism?
• From which vitamin is Coenzyme A derived?
• Why is the thioester bond in Coenzyme A important for its function?

Related terms

Acetyl-CoA:

An important molecule that conveys carbon atoms within the cell for energy production.

Citric Acid Cycle:

A series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetate.

Pantothenic Acid: Also known as vitamin B5, it's a precursor to Coenzyme A.