C-reactive protein (CRP)

Definition

C-reactive protein (CRP) is a substance produced by the liver in response to inflammation. Elevated levels of CRP can indicate inflammation and are often used as a marker for autoimmune disorders.

5 Must Know Facts For Your Next Test

1. CRP levels increase in response to inflammation, infection, and tissue damage.
2. High CRP levels are often found in autoimmune diseases such as rheumatoid arthritis and lupus.
3. CRP is measured through a blood test called the high-sensitivity CRP (hs-CRP) test.
4. Normal CRP levels are typically lower than 10 mg/L, while elevated levels can indicate an underlying inflammatory condition.
5. CRP does not specify the location or cause of inflammation but serves as a general indicator of systemic inflammation.

Review Questions

• What is the primary function of C-reactive protein (CRP) in the body?
• Which autoimmune disorders commonly exhibit elevated CRP levels?
• How is CRP measured and what do elevated levels indicate?

Related terms

Inflammation:

A biological response to harmful stimuli such as pathogens, damaged cells, or irritants.

Autoimmune Disease: A condition where the immune system mistakenly attacks the body's own tissues.

Erythrocyte Sedimentation Rate (ESR): A blood test that measures how quickly red blood cells settle at the bottom of a test tube, indicating inflammation.