Antiserum

Definition

Antiserum is a blood serum containing polyclonal antibodies that can neutralize specific antigens, such as pathogens or toxins. It is used in immunotherapy and diagnostic tests to confer passive immunity or identify substances.

5 Must Know Facts For Your Next Test

1. Antiserum can provide immediate but temporary immunity by supplying pre-formed antibodies.
2. It is typically derived from the blood of humans or animals that have been exposed to the antigen.
3. Polyclonal antibodies in antiserum can recognize multiple epitopes on a single antigen.
4. Antiserum is crucial in treating snake bites, certain infections, and toxin exposures.
5. The production of antiserum involves immunizing an animal, collecting its serum, and purifying the antibodies.

Review Questions

• What are the primary uses of antiserum in medical treatments?
• How does antiserum differ from monoclonal antibody therapies?
• Explain the process involved in producing antiserum.

Related terms

Polyclonal Antibodies:

Antibodies produced by different B cell lineages within the body, recognizing multiple epitopes.

Monoclonal Antibodies:

Antibodies derived from a single B cell clone, specific to a single epitope.

Passive Immunity:

Immunity conferred by transferring pre-formed antibodies from an immune individual to a non-immune individual.