Microbiology

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Antigen binding

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Microbiology

Definition

Antigen binding is the specific interaction between an antigen and an antibody or a receptor on a lymphocyte. This interaction is crucial for the immune system to recognize and neutralize pathogens.

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5 Must Know Facts For Your Next Test

  1. Antigen binding sites are located on the variable regions of antibodies.
  2. The strength of antigen binding is referred to as affinity.
  3. T cells have receptors (TCRs) that bind to antigens presented by MHC molecules.
  4. B cells can bind directly to free-floating antigens through their B cell receptors (BCRs).
  5. Cross-reactivity can occur when an antibody binds to similar epitopes on different antigens.

Review Questions

  • What is the role of the variable region in antigen binding?
  • How do T cells recognize antigens?
  • What is cross-reactivity in the context of antigen binding?

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