Anaplasma phagocytophilum

Definition

Anaplasma phagocytophilum is a gram-negative bacterium that infects white blood cells and is the causative agent of anaplasmosis. It is primarily transmitted to humans through tick bites.

5 Must Know Facts For Your Next Test

1. Anaplasma phagocytophilum is most commonly transmitted by Ixodes ticks, including the deer tick.
2. The bacterium targets neutrophils, a type of white blood cell, compromising the immune system.
3. Symptoms of anaplasmosis include fever, headache, muscle pain, and sometimes severe complications like respiratory failure.
4. Diagnosis is typically confirmed through serological tests or PCR (polymerase chain reaction).
5. Treatment often involves antibiotics such as doxycycline.

Review Questions

• What type of cell does Anaplasma phagocytophilum primarily infect?
• Which ticks are known to transmit Anaplasma phagocytophilum to humans?
• What are common symptoms associated with anaplasmosis?

Related terms

Ixodes tick:

A genus of ticks that includes species responsible for transmitting many pathogens to humans.

Doxycycline:

An antibiotic commonly used to treat bacterial infections including those caused by Anaplasma phagocytophilum.

Serological test: A diagnostic examination involving the detection of antibodies in the blood.