Parafollicular cells

Definition

Parafollicular cells, also known as C-cells, are specialized cells located in the thyroid gland. They secrete the hormone calcitonin, which helps regulate calcium levels in the blood.

5 Must Know Facts For Your Next Test

1. Parafollicular cells are located in the thyroid gland.
2. They secrete the hormone calcitonin.
3. Calcitonin helps lower blood calcium levels by inhibiting bone resorption.
4. Parafollicular cells are derived from neural crest cells during embryonic development.
5. These cells play a role in maintaining calcium homeostasis alongside parathyroid hormone (PTH).

Review Questions

• What hormone is secreted by parafollicular cells?
• Where are parafollicular cells located?
• How do parafollicular cells contribute to calcium homeostasis?

Related terms

Thyroid Gland:

A butterfly-shaped endocrine gland located in the neck that produces hormones regulating metabolism and growth.

Calcitonin:

A hormone produced by parafollicular cells that helps lower blood calcium levels.

Parathyroid Hormone (PTH): A hormone secreted by the parathyroid glands that raises blood calcium levels by stimulating bone resorption and increasing calcium absorption in the kidneys and intestines.