Chromosome

Definition

A chromosome is a structure made of DNA and proteins that carries genetic information. Each chromosome consists of a single, long DNA molecule wrapped around histone proteins, forming a compact and organized unit that plays a critical role during cell division, inheritance, and reproduction.

5 Must Know Facts For Your Next Test

1. Humans have 46 chromosomes, arranged in 23 pairs, with one chromosome of each pair inherited from each parent.
2. Chromosomes become highly condensed and visible under a microscope during cell division, specifically during metaphase, facilitating the accurate distribution of genetic material.
3. Each chromosome has a specific location called the centromere that plays a vital role in the movement of chromosomes during cell division.
4. Chromosomal abnormalities can lead to inherited disorders or conditions, such as Down syndrome, which results from an extra copy of chromosome 21.
5. During asexual reproduction, organisms often replicate their chromosomes to ensure the offspring are genetically identical to the parent.

Review Questions

• How do chromosomes contribute to genetic variation during cell division?
  • Chromosomes play a crucial role in genetic variation during cell division through processes like meiosis, where homologous chromosomes exchange genetic material through crossing over. This shuffling of genetic information leads to unique combinations of genes in gametes. As these gametes fuse during fertilization, the resulting offspring inherit different sets of chromosomes, contributing to diversity within a population.
• Discuss how chromosomal abnormalities can lead to inherited disorders and provide an example.
  • Chromosomal abnormalities occur when there is an alteration in the number or structure of chromosomes, which can disrupt normal gene function. For instance, Down syndrome is caused by trisomy 21, where individuals have three copies of chromosome 21 instead of the usual two. This extra genetic material alters development and can lead to various physical and intellectual challenges.
• Evaluate the role of chromosomes in asexual reproduction compared to sexual reproduction.
  • In asexual reproduction, organisms rely on mitosis to replicate their chromosomes, ensuring that the offspring have identical genetic material as the parent. This method allows for rapid population increase but limits genetic diversity. In contrast, sexual reproduction involves meiosis and fertilization, which introduce genetic variation by combining different sets of chromosomes from two parents. This variation is crucial for adaptation and evolution within species, showcasing how chromosomes serve different functions depending on the mode of reproduction.

Related terms

DNA: Deoxyribonucleic acid (DNA) is the molecule that contains the genetic instructions for the development and functioning of living organisms.

Gene: A gene is a specific segment of DNA that contains the instructions for making a particular protein or set of proteins, influencing traits and characteristics.

Mitosis: Mitosis is a type of cell division that results in two genetically identical daughter cells, allowing for growth and repair of tissues.