Autoimmunity

Definition

Autoimmunity is a condition where the immune system mistakenly attacks the body's own tissues. This can lead to various autoimmune diseases, such as rheumatoid arthritis and lupus.

5 Must Know Facts For Your Next Test

1. Autoimmune diseases occur when the immune system fails to distinguish between self and non-self antigens.
2. Common autoimmune diseases include multiple sclerosis, type 1 diabetes, and Hashimoto's thyroiditis.
3. Genetic factors and environmental triggers like infections or stress can contribute to the development of autoimmunity.
4. Autoimmunity involves both the innate and adaptive immune systems.
5. Treatments for autoimmune diseases often include immunosuppressive drugs to reduce immune system activity.

Review Questions

• What is autoimmunity and how does it affect the body?
• Name three common autoimmune diseases.
• What are some factors that can trigger autoimmunity?

Related terms

Antigen: A substance that induces an immune response in the body, especially the production of antibodies.

Immunosuppressive Drugs: Medications used to reduce or suppress the strength of the body's immune system.

Innate Immune System: The part of the immune system that serves as a first line of defense against pathogens through non-specific responses.