AP US History
The term 'West of Mississippi' refers to the vast region of land located west of the Mississippi River, which became increasingly significant in American history during the early 19th century. This area was integral to various political, economic, and social developments, particularly in relation to westward expansion, federal power, and the evolving dynamics between the federal government and the states. The shift in focus to this territory marked a critical phase in the nation’s growth and its interactions with Native American tribes.