Renin

Definition

Renin is an enzyme secreted by the juxtaglomerular cells of the kidneys in response to low blood pressure or decreased sodium chloride concentration. It plays a critical role in the body's regulation of blood pressure, electrolyte balance, and fluid volume.

Related terms

Juxtaglomerular cells: Specialized cells located in the kidneys that sense blood pressure changes and release renin accordingly.

Angiotensin II: A potent vasoconstrictor formed from angiotensin I through the action of angiotensin-converting enzyme (ACE), primarily involved in blood pressure regulation and stimulated by renin activity.

Aldosterone: A hormone secreted by the adrenal glands that increases sodium reabsorption in the kidneys, whose secretion is partly regulated by angiotensin II, stimulated by renin