5.1 Generalized Anxiety Disorder and Panic Disorder

3 min readjuly 9, 2024

Anxiety disorders can wreak havoc on daily life. (GAD) involves persistent worry about various aspects of life, while is marked by sudden, intense . Both can lead to , avoidance behaviors, and significant life disruptions.

The outlines specific criteria for diagnosing these disorders. GAD requires for at least 6 months, while Panic Disorder involves recurrent panic attacks followed by . Understanding these distinctions is crucial for proper diagnosis and treatment.

Generalized Anxiety Disorder (GAD) and Panic Disorder

Generalized anxiety vs panic disorder

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  • Generalized Anxiety Disorder (GAD)
    • Characterized by persistent and excessive worry about various aspects of life (work, health, finances) that is difficult to control
    • Anxiety is not focused on a specific object or situation but rather generalized across multiple domains
    • Accompanied by physical symptoms such as , , and
  • Panic Disorder
    • Marked by recurrent unexpected panic attacks that involve intense fear or discomfort peaking within minutes
    • Panic attacks are accompanied by physical symptoms (palpitations, sweating, trembling) and (fear of losing control or dying)
    • Concern about additional attacks or their consequences leads to significant maladaptive changes in behavior (avoidance of certain situations)

DSM-5 criteria for anxiety disorders

  • GAD diagnostic criteria
    • Excessive anxiety and worry occurring more days than not for at least 6 months about a number of events or activities
    • Difficulty controlling worry that is associated with at least three of the following symptoms:
      1. Restlessness or feeling keyed up or on edge
      2. Being easily fatigued
      3. Difficulty concentrating or mind going blank
      4. Irritability
      5. Muscle tension
      6. (difficulty falling or staying asleep, or restless unsatisfying sleep)
    • Symptoms cause clinically significant distress or impairment in social, occupational, or other important areas of functioning
  • Panic disorder diagnostic criteria
    • Recurrent unexpected panic attacks that involve abrupt feelings of intense fear or discomfort that peak within minutes
    • At least one attack followed by 1 month or more of:
      1. Persistent concern or worry about additional panic attacks or their consequences (losing control, having a heart attack)
      2. Significant maladaptive change in behavior related to the attacks (avoidance of unfamiliar situations)
    • Attacks not attributable to the physiological effects of a substance (caffeine) or another medical condition ()

Symptoms of anxiety disorders

  • GAD symptoms
    • Physical: muscle tension, fatigue, restlessness, difficulty sleeping, stomachaches, headaches
    • Cognitive: excessive worry that is difficult to control, difficulty concentrating, mind going blank, indecisiveness
    • Behavioral: avoidance of anxiety-provoking situations, procrastination, seeking reassurance from others
  • Panic disorder symptoms
    • Physical: palpitations, sweating, trembling, shortness of breath, chest pain, nausea, dizziness, chills or heat sensations
    • Cognitive: fear of losing control or going crazy, fear of dying, (feelings of unreality), (feeling detached from oneself)
    • Behavioral: avoidance of situations that may trigger panic attacks (driving, crowded places), reliance on safety behaviors (always having an escape route or access to medication)

Impact of anxiety on daily life

  • GAD impact
    • Decreased work performance and productivity due to difficulty concentrating and fatigue
    • Strained interpersonal relationships as a result of irritability and excessive reassurance-seeking
    • Reduced participation in social activities leading to isolation and loneliness
    • Increased healthcare utilization and costs due to frequent doctor visits for physical symptoms
    • Diminished overall quality of life and sense of well-being
  • Panic disorder impact
    • Avoidance of places or situations where panic attacks have occurred (shopping malls, public transportation) resulting in restricted travel or social activities
    • Increased risk of unemployment or underemployment due to avoidance behaviors and decreased functioning
    • Impaired social and occupational functioning leading to strained relationships and decreased job performance
    • Decreased quality of life and increased disability, often accompanied by and other co-occurring disorders
    • Increased healthcare costs due to emergency room visits for panic attacks and frequent medical evaluations for physical symptoms

Key Terms to Review (25)

Adolescents: Adolescents are individuals typically aged between 10 to 19 years who are in a developmental stage marked by significant physical, emotional, and social changes. This period is crucial for establishing identity and coping with various pressures, which can contribute to the emergence of mental health disorders, including anxiety, compulsions, body image issues, and mood disorders.
Amygdala: The amygdala is a small, almond-shaped cluster of nuclei located deep within the temporal lobes of the brain, primarily associated with processing emotions, particularly fear and pleasure. It plays a crucial role in the formation and storage of memories related to emotional events, influencing how individuals respond to threats and stressors.
Avoidance Behavior: Avoidance behavior is a coping mechanism where individuals steer clear of situations, activities, or stimuli that trigger anxiety or distress. This behavior is often reinforced by the temporary relief it provides from uncomfortable feelings, leading to a cycle where the avoidance becomes more pronounced over time. It plays a critical role in various psychological conditions, particularly those characterized by anxiety and fear.
Cognitive symptoms: Cognitive symptoms refer to difficulties in mental processes such as thinking, understanding, learning, and remembering. These symptoms can significantly impact a person's ability to function in daily life, influencing their decision-making, perception of reality, and overall mental health. In the context of anxiety disorders and schizophrenia, cognitive symptoms play a crucial role in how individuals experience and cope with their conditions.
Depersonalization: Depersonalization is a dissociative experience where an individual feels detached from their own thoughts, body, or surroundings, as if they are an observer of themselves. This can create a sense of unreality, leading to feelings of disconnection and anxiety. It's often related to high levels of stress or anxiety, and can manifest in people experiencing generalized anxiety disorder or panic disorder, where intense feelings of fear and anxiety may trigger these dissociative episodes.
Depression: Depression is a common and serious mental health disorder characterized by persistent feelings of sadness, hopelessness, and a lack of interest or pleasure in activities. It can significantly impair daily functioning and is often linked to various biological, psychological, and social factors that contribute to its onset and maintenance.
Derealization: Derealization is a dissociative symptom characterized by a sense of detachment from one’s surroundings, making the external world feel unreal or distorted. This experience can lead to feelings of disconnection from reality, which can be unsettling and distressing for those who experience it. In the context of anxiety disorders, derealization often accompanies heightened anxiety or panic, contributing to a cycle of fear and confusion.
DSM-5: The DSM-5, or Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, is a comprehensive classification system used by mental health professionals to diagnose mental disorders. It provides standardized criteria and diagnostic guidelines that enhance the reliability of assessments and treatment plans across different practitioners, while also addressing various dimensions such as symptom severity and duration.
Excessive Worry: Excessive worry is a persistent and uncontrollable feeling of anxiety or apprehension about potential future events or outcomes. This kind of worry goes beyond the normal level of concern and can significantly impair daily functioning, leading to emotional distress and physical symptoms. It is a key feature of certain anxiety disorders, particularly in the context of chronic anxiety experiences, where individuals struggle to manage their thoughts and fears effectively.
Fatigue: Fatigue refers to a state of physical or mental weariness that can significantly impact an individual's ability to function effectively. In the context of certain psychological conditions, fatigue can manifest as an overwhelming lack of energy and motivation, often influencing emotional and cognitive processes. This sensation is not merely tiredness but can be a debilitating symptom associated with heightened anxiety, depressive states, and overall diminished quality of life.
Fight or Flight Response: The fight or flight response is a physiological reaction that occurs in response to a perceived threat, triggering the body's sympathetic nervous system to prepare for either confrontation or escape. This response leads to various physical changes, such as increased heart rate, heightened senses, and adrenaline release, which are crucial for survival in dangerous situations. It plays a significant role in understanding how anxiety disorders and stress-related conditions manifest, affecting individuals' emotional and physical health.
Generalized Anxiety Disorder: Generalized Anxiety Disorder (GAD) is a mental health condition characterized by excessive, uncontrollable worry about various aspects of daily life, such as work, health, and social interactions. This ongoing anxiety can lead to physical symptoms like restlessness, fatigue, and difficulty concentrating, impacting overall quality of life. GAD often coexists with other anxiety disorders and can influence behaviors associated with avoidance, phobias, and even non-suicidal self-injury as individuals seek to cope with overwhelming feelings.
Hyperthyroidism: Hyperthyroidism is a condition characterized by an overproduction of thyroid hormones, leading to an accelerated metabolism and various physiological effects. This condition can result in symptoms such as increased heart rate, anxiety, irritability, and weight loss, which can often be mistaken for or exacerbate anxiety disorders, including generalized anxiety disorder and panic disorder. The relationship between hyperthyroidism and these anxiety-related conditions is important to understand, as the physiological changes caused by elevated thyroid hormones can mimic or intensify anxiety symptoms.
Muscle Tension: Muscle tension refers to the state of increased firmness and tightness in skeletal muscles, often resulting from stress, anxiety, or physical strain. This physiological response is commonly observed in individuals experiencing heightened anxiety levels or panic attacks, as the body prepares for a 'fight or flight' response. Muscle tension can lead to discomfort, pain, and various physical symptoms, making it an essential aspect of understanding anxiety-related disorders.
Panic Attack Symptoms: Panic attack symptoms are a range of physical and psychological reactions that occur suddenly and intensely, often without warning. These symptoms include heart palpitations, shortness of breath, dizziness, feelings of unreality, and overwhelming fear. Understanding these symptoms is crucial in recognizing panic attacks and distinguishing them from other anxiety-related disorders, particularly in the context of generalized anxiety disorder and panic disorder.
Panic Attacks: Panic attacks are sudden episodes of intense fear or discomfort that peak within minutes and can involve a variety of physical and emotional symptoms. These can include rapid heart rate, shortness of breath, dizziness, sweating, and feelings of impending doom. The experience can be so overwhelming that individuals may fear losing control or even dying, linking panic attacks to broader anxiety disorders, which impact daily functioning and quality of life.
Panic Disorder: Panic disorder is a type of anxiety disorder characterized by recurrent and unexpected panic attacks, which are sudden periods of intense fear or discomfort that reach a peak within minutes. These panic attacks often lead to persistent concern about experiencing more attacks, resulting in significant changes in behavior or avoidance of situations that might trigger an attack. This disorder is closely related to generalized anxiety disorder and can impact a person's daily life and well-being.
Persistent Concern: Persistent concern refers to the ongoing and excessive worry or anxiety about various aspects of life that individuals experience. This state is often a hallmark of anxiety disorders, particularly those characterized by an inability to control worry, leading to significant distress and impairment in daily functioning. In the context of anxiety disorders, persistent concern can manifest as a chronic preoccupation with potential threats or dangers, making it difficult for individuals to relax or feel at ease.
Physical Symptoms: Physical symptoms are bodily sensations or changes that occur as a result of psychological conditions, often manifesting in ways that can be physically felt or observed. In the context of anxiety disorders, these symptoms can include heart palpitations, sweating, trembling, and gastrointestinal disturbances, and they play a critical role in how individuals experience and interpret their anxiety. Understanding these symptoms is essential for recognizing the connection between mental states and physical health, especially in conditions where anxiety significantly impacts daily functioning.
Restlessness: Restlessness refers to a state of agitation or inability to relax, often characterized by an overwhelming sense of unease or constant movement. This feeling is commonly associated with anxiety disorders, as individuals may struggle to sit still or focus due to persistent worry or fear. Restlessness can manifest in both physical and mental ways, impacting daily functioning and overall well-being.
Serotonin: Serotonin is a neurotransmitter that plays a critical role in regulating mood, anxiety, and various physiological functions such as sleep and appetite. It is often referred to as the 'feel-good' chemical because of its influence on feelings of happiness and well-being, and is closely connected to various psychological disorders and treatments.
Sleep Disturbance: Sleep disturbance refers to a range of issues that disrupt normal sleep patterns, leading to difficulty in falling asleep, staying asleep, or experiencing restful sleep. These disturbances can significantly impact mental health, often exacerbating conditions such as anxiety and panic disorders, which are characterized by heightened states of worry and fear that can interfere with the ability to relax and fall asleep.
Substance Use Disorder: Substance use disorder is a complex condition characterized by an individual's inability to control their use of a substance despite harmful consequences. This disorder can lead to significant impairment in personal, social, and occupational functioning. It often co-occurs with various mental health issues, including anxiety and PTSD, making it a crucial aspect to understand when examining the interplay between substance use and mental health disorders.
Women: In the context of mental health, women refer to individuals who identify as female and often experience unique psychological challenges and disorders, including Generalized Anxiety Disorder and Panic Disorder. These challenges can be influenced by biological, social, and cultural factors that differ from those affecting men, leading to different manifestations and coping strategies in anxiety-related conditions.
Worry Criteria: Worry criteria refer to the specific characteristics and patterns of worry that are observed in individuals with anxiety disorders, particularly in generalized anxiety disorder and panic disorder. These criteria help to distinguish excessive worry from normal concerns, focusing on the persistent, uncontrollable nature of worry that can lead to significant distress or impairment. Understanding worry criteria is crucial for identifying and diagnosing these disorders, as they underscore the role that chronic worry plays in the overall experience of anxiety.
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